Could CBD Protect Brain Against Neurodegenerative Diseases?
While more research is needed, a new study indicates that CBD provides capacity for neuroprotection against degenerative diseases, such as Alzheimer’s and Parkinson’s.
In 2003, a patent for the neuroprotective potential of non-psychoactive cannabinoids had been issued to the U.S. Department of Health and Human Services. A federal government branch that classifies marijuana as an illicit substance with with no accepted medical value, has technology rights to CBD’s ability to protect the brain.
“Cannabinoids are considered to have a particular application as neuroprotectants, for example in the limitation of neurological damage after ischemic injuries such as stroke and fracture or in the treatment of neurodegenerative diseases,” states patent No. 6,630,507.
A new study published last month by Korean scientists in the journal Marijuana and Cannabinoid Science attempted dive deeper. Although this patent is owned by the federal government, the scientific community has published mixed results on this phenomenon. Variables such as types of brain cells and experimental environments have resulted in “specific and somewhat conflicting findings,” the researchers wrote, with the goal of knowing whether or not CBD has any ability to shield brain cells from oxidative stress.
The response, it turns out, is yes — there is a possible link between CBD and slowing death of brain cells.
“The use of low concentration CBD has greatly saved the neurons from oxidative stress and established their potential for neuroprotection,” researchers concluded.
Researchers tested what effects differing levels of CBD molecules had on hydrogen peroxide (H2O), or oxidative stress, for the analysis. In neurodegenerative diseases such as Alzheimer’s, Parkinson’s, Huntington’s, and ALS the enzyme is known to be a pathological culprit.
Tested under “in vitro” conditions or in a petri dish, researchers found that CBD’s antioxidant properties supplied hippocampal neurons with a defensive layering induced by oxidative stress from the initiation and development of apoptosis, or cell death.
Researchers, involved, recognised the need for more study, as the brain comprises complex structures and networks that could affect these findings. They added possible avenues of further research regarding CBD administration – That is, whether taking CBD by drinking, eating foods or applying them topically could have an influence on the brain. But the study concluded that CBD does have neuroprotective properties worth investigating further.
Bures, :., 2020. Study Confirms CBD Could Protect Brain Against Neurodegenerative Diseases – The Fresh Toast. [online] The Fresh Toast. Available at: <https://thefreshtoast.com/cannabis/study-confirms-cbd-could-protect-brain-against-neurodegenerative-diseases/> [Accessed 11 March 2020].